Docking of mol2 SDF format

Hello,

I've been docking compound (http://zinc.docking.org/substance/2037933)
in two different formats mol2 and SDF and I have totally different results.
Could anyone help me to understand why it happens? I'm new in docking..

Thanks in advance,

Patrycja

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more info

Thanks for your question. To answer it, I would need to know more. Which program, which options? Do the mol2 and SDF superpose? What is the difference in energy? If you are doing conformational sampling of the ligand, is the stereochemistry on the ribose preserved?

-- sent from my iZINC

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